What may occur when using Progesterone Cream for the first time

It is most important that you understand and are aware of certain symptoms which may be experienced when using progesterone cream for the first time.

People react differently to certain things, what may cause you discomfort, will not to others. You may experience 'adverse' symptoms often encountered by men and women if they have a naturally high level of estrogen or, in the case of women, who have been on HRT (hormone replacement therapy) or the contraceptive Pill for any length of time and therefore have low progesterone levels. In some cases you may feel an ache or a pain in your joints, or you may retain water, or put on some weight. Please persevere with the progesterone cream, DO NOT stop using it as these uncomfortable symptoms should clear up within a week IF used as suggested.

As you use progesterone it will gradually become the dominant hormone which is what is needed. As this happens symptoms begin to ease.

Some women never experience estrogen dominance, in others it can take several days, whilst in others it can last longer. Much depends on the amount of excess estrogen that is present. Men can also experience estrogen dominance when first using progesterone.

You are estrogen dominant if you experience some of the symptoms listed below.

Men also experience these symptoms apart from the obvious women's problems

* aches and pains
* anger
* bleeding which comes either earlier or later than usual
* bloating/weight gain due to water retention
* breast tenderness
* bruising
* constipation
* dizziness
* headaches
* heart palpitations
* hot flushes
* hypoglycaemia
* increased appetite/cravings
* irritation
* migraines
* mild depression
* mood swings
* muscle weakness
* nausea
* skin problems/acne/melasma
* spotting
* tiredness/chronic fatigue

If you experience any of these symptoms then your choice is to either...

* increase the dose and persevere with the symptoms, or
* reduce the dose considerably to begin with and then gradually increase it over a month or two. This will understandably take longer to resolve symptoms

Please follow these instructions when using progesterone cream for the first time

1. If you no longer follow a monthly cycle and are experiencing menopausal symptoms i.e. hot flushes etc, progesterone cream must be used every day.

  • Please use 6ml or 1 heaped teaspoon per day - 3ml in the morning and 3ml at night. Use this amount for 5 days, then slowly start to reduce.
    If you reduce too quickly you will soon know about it as your symptoms will return. Should this happen simply increase your dose again and stay on that for a few more days, then reduce again at a slower rate.

  •  The aim is to reach 3ml per day - 1 1/2ml in the morning and 1 1/2 at night.

  •  It is not recommended that you use progesterone cream all at once as we want to keep the progesterone levels even.

  •  If any of your symptoms return, up your dose, only you can decide on the required amount for you.

  •  The main thing is to NOT use less than the required 3ml a day once your symptoms have disappeared.


2. If you are peri-menopause and suffering from irregular bleeding please use progesterone cream as per (1) above and follow the same instructions.

  •  Your bleeding could normalise or will stop altogether as you head into menopause.

3. If you follow a monthly cycle please use progesterone cream by following your same monthly cycle. i.e. if you have a 28 day cycle then you will start the cream 14 days BEFORE your period begins. 

If you do not follow the above instructions it will not work and you will think that the progesterone cream is rubbish which is totally untrue!